Myelin sheath

Stratum myelini

NervousNervesWhole body

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What it is
Segments of fatty insulation wrapped around the axon in dozens of tight spiral layers - made by Schwann cells in peripheral nerves and by oligodendrocytes in the brain and spinal cord.
Function
Insulates the axon so the impulse jumps from gap to gap (saltatory conduction), raising conduction speed from about 1 m/s to as much as 120 m/s.
Size
Each internode 0.2-2 mm long; sheath up to ~2 micrometres thick
Clinical note
Multiple sclerosis strips myelin in the brain and cord; Guillain-Barre syndrome attacks peripheral myelin, causing rapidly ascending weakness.