Arachnoid mater

Arachnoidea mater cranialis

NervousOrgansHead

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What it is
The thin, cobweb-like middle membrane lying against the inner dura. Fine trabeculae cross the CSF-filled subarachnoid space beneath it to the pia mater, which clings to every gyrus and sulcus of the brain surface.
Function
Encloses the subarachnoid space where CSF cushions the brain and the large cerebral arteries run; arachnoid granulations return CSF to the venous sinuses.
Size
Microscopically thin (tens of micrometres); subarachnoid space holds ~125-150 ml of CSF in total
Clinical note
A ruptured berry aneurysm bleeds into the subarachnoid space, classically causing a sudden "worst headache of my life"; meningitis inflames the arachnoid and pia.