Distal convoluted tubule (magnified)

Tubulus contortus distalis

UrinaryOrgansWhole body

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What it is
Short coiled tubule in the cortex that begins at the macula densa, where the tubule touches its own glomerulus to form the juxtaglomerular apparatus, and drains via a connecting tubule into a collecting duct.
Function
Fine-tunes sodium, chloride and calcium reabsorption (thiazide-sensitive NCC cotransporter; calcium under parathyroid hormone control).
Size
About 5 mm long.
Clinical note
The macula densa senses tubular salt and signals the neighbouring cells to release renin when it falls.